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View Journal Article: Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS) for High-Throughput Characterization of Biosurfaces

Citation: Roberson, Sonya, Sehgal, Amit, Fahey, A. and Karim, Alamgir (2003). Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS) for High-Throughput Characterization of Biosurfaces. Applied Surface Science 203-204 (). 855-858.
Collection: Polymer Publications  
 
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Title Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS) for High-Throughput Characterization of Biosurfaces
Author(s) Roberson, Sonya
Sehgal, Amit
Fahey, A.
Karim, Alamgir
Keyword(s) combinatorial methods
TOF-SIMS
UV-ozone treatment
Surface energy gradient
Poly(ε-caprolactone)
Osteoblast cells
Polymers
Abstract/Summary A graded oxidation process, involving UV-ozone (UVO) treatment, was used to create a poly(ε-caprolactone) (PCL) surface with a systematic variation in surface chemistry. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has proved useful in characterizing the chemical composition of these surfaces and in monitoring the oxidation process. The TOF-SIMS data correlates with contact angle data and the results of the binding studies performed with mouse calvarial cells. UVO treatment resulted in a PCL surface with improved wettability and cellular adhesion. © 2002 Elsevier Science B.V. All rights reserved.
Publisher Elsevier
Date 2003-01-01
Copyright Notice http://www.nist.gov/public_affairs/disclaim.htm
Journal Applied Surface Science
Volume 203-204
Pages 855-858
Copyright Agreement on
Additional Notes Applied Surface Science 2003, 203-204, 855-858
 
 
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Created: Tue, 31 Oct 2006, 00:58:01 EST Detailed History


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