Red blood cell aggregation is currently of basic scientific and clinical interest because the mechanism behind aggregation is not well understood and it is linked with disease. Red
blood cells aggregate, in the presence of a cosolute, to form structures called rouleaux. The theory that depletion interaction was responsible for this aggregation was studied in relation to the
importance of cell deformability. Various polymer solutions were tested as our cosolute, for the ideal polymer, molecular weight, and concentration. The importance of the deformability of red blood
cells was studied by adding spherical particles to the red blood cell polymer solution and observing different structures.
Publisher
Cornell Center for Materials Research
Date
2004-08-17
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Support for this REU program is provided through the National Science Foundation Materials Research Science and Engineering Centers (MRSEC) Program (DMR-0079992) and the REU-Site
program (DMR-0097494). Additional funding is provided by Cornell University.
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